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Cayman Chemical SURVODUTIDE 10MG
Supplier: Cayman Chemical 4097210 MG
A dual peptide agonist of GLP-1R and GCGR; increases cAMP accumulation in CHO-K1 cells expressing GLP-1R or GCGR in reporter assays (EC50s = 0.33 and 0.52 nM, respectively); potentiates glucose-induced insulin secretion in isolated mouse, rat, and perifused human pancreatic islets; reduces body weight and food intake in diet-induced obese mice at 3 and 30 nmol/kg per day; reduces the levels of hepatic triglycerides and cholesterol, as well as plasma levels of glucagon, cholesterol, triglycerides, ALT, AST, insulin, and leptin in diet-induced obese mice; increases energy expenditure in diet-induced obese mice at 10 nmol/kg per day
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