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AdipoGen Swinholide A (10 µg)
Supplier: AdipoGen AGCN20035C010
Swinholide A (10 µg), AdipoGen Life Sciences. Chemical. CAS: 95927-67-6. Formula: C78H132O20. MW: 1389.9. Isolated from marine sponge Theonella swinhoei. Cell permeable dimeric dilactone macrolide. Cytotoxic compound. Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin). Depolymerizes actin filaments (F-actin). Antifungal. Apoptosis inducer. Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription.
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