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Sigma Aldrich Fine Chemicals Biosciences SygRNAR Cas9 Synthetic tra
Supplier: Sigma Aldrich Fine Chemicals Biosciences TRACRRNA05N5NMOL

The SygRNA(R) synthetic RNA system recruits SpCas9 nuclease to specific genomic targets. The tracrRNA (trans-activating crRNA) binds to a crRNA (CRISPR RNA) and the resulting crRNA-tracrRNA complex guides Cas9 protein to crRNA-specified sites in the genome. SygRNA(R) synthetic tracrRNA and crRNAs are optimized for use with Cas9 expressing of cell lines Cas9 protein or Cas9 mRNA and compatible with a variety of delivery methods such as microinjection lipofection and electroporation.
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