U-Blot Pan-Symmetric Di-Methyl Arginine Rabbit mAb is a Rabbit-derived recombinant monoclonal antibody (clone W-R24) that specifically recognizes Symmetric Di-Methyl Arginine a symmetric dimethylation of arginine modification at Arg(R) It shows reactivity with Human Mouse Rat Validated applications include WB IHC-P ICC/IF Recommended dilutions WB 1500-1000 IHC-P 1200-11000 ICC/IF 1100-200 Purified by protein a Histones and non-histone proteins are subjected to a variety of enzyme-catalyzed post-translational modifications including acetylation methylation phosphorylation and ubiquitination Symmetric dimethyl arginine (SDMA) is an important arginine methylation mark catalyzed primarily by type II protein arginine methyltransferases It is widely distributed in eukaryotic cells and abundantly present in chromatin proteins RNA-binding factors and signal transduction molecules Supplied as 100 uL