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Invitrogen™ Human Syndecan 1 (SDC1) ELISA Kit

Catalog No. EHSDC1X10
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EHSDC1X10 10 x 96 Tests
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ELISA

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
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Specifications

Accession Number P18827
Assay Range 16.38 to 4000 pg/mL
Assay Sensitivity 14 pg/mL
Conjugate HRP
Product Type ELISA
Sample Type Plasma, Serum, Supernatant
For Use With (Equipment) Colorimetric Microplate Reader
Gene ID (Entrez) 6382
Gene Symbol Sdc1
Interassay CV <12%
Intraassay CV <10
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
Label or Dye HRP
Quantity 10 x 96 Tests
Regulatory Status RUO
Sample Volume Plasma 15 μL, Serum 15 μL, Supernatant 100 μL
Storage Requirements 2°C to 8°C
Target CD138 (Syndecan-1)
Test Time 1 hrs 20 mins
Total Assay Time 4 hrs 45 mins
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