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Cayman Chemical SynthetIc AspIrIn 50g
Supplier: Cayman Chemical 7026050 G
An NSAID and a COX-1 and COX-2 inhibitor (IC50s = 4.45 and 13.88 µM, respectively, for the human enzymes); an inhibitor of H-PGDS (IC50 = 750 µM for the ovine enzyme); inhibits epinephrine- and ADP-induced platelet aggregation at 6 UG/ml; reduces infarct volume and microglial infiltration in a rat model of ischemia-reperfusion injury induced by MCAO at 30 mg/kg; decreases macrophage infiltration into, increases the number of smooth muscle cells and levels of collagen in, and reduces the area of, atherosclerotic lesions in LDL receptor-deficient mice fed a high-fat diet in the drinking water at 30 mg/L
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