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Cayman Chemical SynthetIc Obovatol 1mg
Supplier: Cayman Chemical 275531 MG
A lignan polyphenol with diverse biological activities; inhibits epinephrine- or arachidonate-induced aggregation of isolated rat platelets (IC50s = 59 and 54 µM, respectively); induces cell cycle arrest at the S phase and apoptosis in SW620 cancer cells at 50 µM; reduces tumor volume and weight in a SW620 mouse xenograft model at 6 mg/kg per day; decreases hippocampal and cortical Aβ42 fibril formation and reduces latency and distance to escape in the Morris water maze in a Tg2576 mouse model of Alzheimer's disease at 1 mg/kg per day for three months
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