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Cayman Chemical SynthetIc PImodIvIr 10mg
Supplier: Cayman Chemical 2932110 MG
An inhibitor of influenza virus PB2 (KD = ~1.6 µM) and inhibits the activity of Axl and CaMKIIβ by >50% in a panel of 65 human and rat kinases; decreases the replication of seven adamantine- and neuraminidase inhibitor-resistant strains of influenza virus A (EC50s = 50s = 0.58, 0.64, and 0.89, respectively, in a cell-based assay); increases survival in a mouse model of intranasal influenza A infection at 1, 3, and 10 mg/kg twice per day
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