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Cayman Chemical SynthetIc XAV939 1mg
Supplier: Cayman Chemical 135961 MG
A small molecule inhibitor of tankyrase 1 and 2 (IC50 = 11 and 4 nM, respectively); increases the protein levels of the axin-GSK3β complex and promotes the degradation of β-catenin; inhibits colony formation of APC-deficient colorectal cancer cells at 0.33 µM
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