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Medchemexpress LLC T-5342126 | 956507-49-6 | 98.1% | 457.99 g·mol-1 | C25H32ClN3O3 | 10MG
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Catalog No. 5000237622
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T-5342126 is a small-molecule toll-like receptor 4 (TLR4) antagonist for laboratory research. It inhibits LPS-induced nitric oxide production in RAW 264.7 cells (IC50 = 27.8 μM) and reduces LPS-induced IL-8, TNF-α, and IL-6 in isolated human whole blood; it also showed reduced ethanol intake and decreased microglial activation in an ethanol-dependence mouse model.

Catalog No. 50-002-37622 Supplier Medchemexpress LLC Supplier No. HY12378910MG
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T-5342126 is a small-molecule toll-like receptor 4 (TLR4) antagonist for laboratory research. It inhibits LPS-induced nitric oxide production in RAW 264.7 cells (IC50 = 27.8 μM) and reduces LPS-induced IL-8, TNF-α, and IL-6 in isolated human whole blood; it also showed reduced ethanol intake and decreased microglial activation in an ethanol-dependence mouse model.

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