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CPC Scientific H-Met-Ser-Arg-Pro-Ala-Cys-Pro-Asn-Asp-Lys-Tyr-Glu-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific PARP002B
The peptide T1 is the thrombin receptor domain, which functions as a tethered ligand for the receptor itself. T1 is an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor. This peptide has served as model peptide in protein modification and MS studies.ONE-LETTER SEQUENCE: MSRPACPNDKYEMOLECULAR FORMULA: C58H91N17O20S2MOLECULAR WEIGHT:1410.6STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [207553-92-2], RESEARCH AREA: HematologyREFERENCES: J.Doorbar and G.Winter, J. Mol. Biol., 244, 361 (1994); H.Schafberg et al., Br. J. Cancer, 76, 1592 (1997); R.Kaufmann et al., NeuroReport, 9, 709 (1998); H.Y.Tang and D.W.Speicher, Anal. Biochem., 334, 48 (2004); M.C.Sun et al., J. Sep. Sci., 31, 538 (2008)
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