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Apexbio Technology LLC TA 01 1784751-18-3 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B49235.1
TA 01 (CAS 1784751-18-3) is a small molecule inhibitor that targets casein kinase 1 isoforms CK1 and CK1 as well as p38 MAPK It exhibits potent inhibitory activity with IC50 values of approximately 6 4 nM for CK1 6 8 nM for CK1 and 6 7 nM for p38 MAPK Through these actions TA 01 is utilized to investigate cellular signal transduction pathways and regulatory mechanisms of circadian rhythm It is particularly applicable in studies focused on pathophysiological processes associated with CK1 and p38 MAPK signaling including those related to cardiac signaling networks
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