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Apexbio Technology LLC TA 02 1784751-19-4 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B49245.1
TA 02 (CAS 1784751-19-4) is a small molecule inhibitor targeting the p38 MAPK signaling pathway It demonstrates inhibitory activity against p38 MAPK with an IC50 of approximately 20 nM and operates through a mechanism comparable to well-characterized inhibitors such as SB 203580 and SB 202190 In addition to its effects on p38 MAPK TA 02 has been shown to inhibit TGFBR-2 Recent studies suggest that TA 02 influences pharmacological processes associated with cardiac function This compound is suitable for experimental studies investigating p38 MAPK-mediated signaling TGF- receptor pathways and cardiovascular disease mechanisms
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