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Medchemexpress LLC Taccalonolide A | 108885-68-3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYN24165MG

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Taccalonolide A is a microtubule stabilizer, a steroid isolated from Tacca chantrieri. It exhibits cytotoxic and antimalarial activities, causing G2-M accumulation, Bcl-2 phosphorylation, and initiating apoptosis. It is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells.

  • Functions as a microtubule stabilizer
  • Isolated from Tacca chantrieri
  • Exhibits cytotoxic and antimalarial properties
  • Causes G2-M accumulation and Bcl-2 phosphorylation
  • Initiates apoptosis
  • Effective against cell lines overexpressing P-glycoprotein (Pgp)
  • Effective against cell lines overexpressing multidrug resistance protein 7 (MRP7)

Catalog No. 50-004-20457


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