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Enzo Life Sciences TACE substrate II (fluorogenic) (100µg)
SDP

Catalog No. 502011296
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Sensitive fluorogenic substrate for TACE (TNFα converting enzyme, ADAM17). Also cleaved by ADAM10 and likely other ADAMs and MMPs. The kcat/Km of TACE for this substrate is 7-fold higher than for the same peptide with the Mca-Dpa fluorophore-quencher pair. FAM fluorescence is quenched by the TAMRA group until cleavage separates them. Ex.: 485nm, Em.: 535nm, although the following Ex/Em can also be used: 490,494/515,520nm. This substrate is useful for inhibitor screening, kinetic analysis, and cellular activity assay. Alternative name: ADAM17 substrate 2 (fluorogenic). Purity: ≥95% (HPLC). Formulation: Lyophilized. Solubility: Soluble in DMSO. Long Term Storage: -20°C.

Catalog No. 50-201-1296 Supplier Enzo Life Sciences Supplier No. BMLP2280100
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Sensitive fluorogenic substrate for TACE (TNFα converting enzyme, ADAM17). Also cleaved by ADAM10 and likely other ADAMs and MMPs. The kcat/Km of TACE for this substrate is 7-fold higher than for the same peptide with the Mca-Dpa fluorophore-quencher pair. FAM fluorescence is quenched by the TAMRA group until cleavage separates them. Ex.: 485nm, Em.: 535nm, although the following Ex/Em can also be used: 490,494/515,520nm. This substrate is useful for inhibitor screening, kinetic analysis, and cellular activity assay. Alternative name: ADAM17 substrate 2 (fluorogenic). Purity: ≥95% (HPLC). Formulation: Lyophilized. Solubility: Soluble in DMSO. Long Term Storage: -20°C.

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