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Medchemexpress LLC Tacedinaline | 112522-64-2 | 99.3% | C15H15N3O2 | 200 MG

Supplier: Medchemexpress LLC HY50934200MG
Tacedinaline (N-acetyldinaline) is a potent inhibitor of histone deacetylase (HDAC), demonstrating significant antitumor activity in preclinical models. Its mechanism involves the inhibition of histone deacetylation and cell cycle arrest. This compound exhibits marked synergism when combined with antineoplastic agents like gemcitabine in non-small cell lung cancer cell lines.
- Inhibits histone deacetylase (HDAC 1, 2, and 3)
- Shows broad antitumor activity
- Induces cell cycle arrest
- Synergistic with gemcitabine in non-small cell lung cancer
- Inhibits mitogen-stimulated blood lymphocyte proliferation
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