AdipoGen TACI hFc hrec

Supplier:  AdipoGen AG40B00793050

Protein. The extracellular domain of human TACI aa 2-118 is fused at the C-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Endotoxin content <0.01EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Binds to human and mouse BAFF and APRIL. Purity >90% SDS-PAGE. B-cell activating factor belonging to the TNF family receptor BAFF-R, B-cell maturation antigen BCMA, and transmembrane activator and calcium modulator and cyclophilin ligand interactor TACI play critical functions in promoting B-cell survival by engaging the ligands a proliferation-inducing ligand APRIL and/or BAFF. TACI is predominantly expressed on peripheral blood B cells and interacts with the B cell activating factor BAFF of ligands and a proliferation inducing ligand APRIL, which are expressed by numerous cell types, including dendritic cells, macrophages and neutrophils.

Catalog No. 50-256-2927