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Apexbio Technology LLC TAE226 (NVP-TAE226) 761437-28-9 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A85575.1

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TAE226 (NVP-TAE226 CAS 761437-28-9) is a selective inhibitor targeting focal adhesion kinase (FAK) with an IC50 of 5 5 nM and it also inhibits the related protein tyrosine kinase Pyk2 (IC50 3 5 nM) By suppressing FAK activity crucial for cell adhesion and migration TAE226 influences cellular processes associated with tumor progression Studies using glioma cells (including U87 and variants) and medullary thyroid carcinoma line MZ-CRC-1 revealed that TAE226 decreases cell proliferation invasion and induces apoptosis highlighting its potential value in cancer research

Catalog No. 50-000-61789


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