Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC TAK-285 | 871026-44-7 | C26H25ClF3N5O3 | 50 MG
Supplier: Medchemexpress LLC HY1519650MG
TAK-285 is a potent, selective, ATP-competitive, and orally active inhibitor of HER2 and EGFR (HER1), with IC50 values of 17 nM and 23 nM, respectively. It demonstrates greater than 10-fold selectivity for HER1/2 compared to HER4, and exhibits less potency against MEK1/5, c-Met, Aurora B, Lck, and CSK, among others. This compound has shown effective antitumor activity and can cross the blood-brain barrier (BBB).
- Potent and selective inhibition
- ATP-competitive
- Orally active
- Antitumor activity
- Blood-brain barrier penetration
- Inhibitory activity against BT-474 cells
- Preclinical efficacy in xenograft models
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?