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Cayman Chemical Takeda-103A 10mg
Supplier: Cayman Chemical 4102710 MG
A GRK2 inhibitor; selectively inhibits phosphorylation of bovine rod outer segments by GRK2 (IC50 = 54 nM) over phosphorylation by GRK1 and GRK5 at concentrations up to 125 µM; inhibits phosphorylation of bovine rod outer segments by GRK2 containing various mutations, including GRK2L271M, GRK2Y206S, GRK2I197L, and GRK2L235G (IC50s = 24, 55, 106, and 180 nM, respectively)
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