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Apexbio Technology LLC Talabostat mesylate 150080-09-4 10mg
Supplier: Apexbio Technology LLC B394110
Talabostat mesylate (CAS 150080-09-4) also known as PT-100 or Val-boroPro is an orally active inhibitor targeting dipeptidyl peptidase enzymes particularly dipeptidyl peptidase IV (DPP4) and fibroblast activation protein (FAP) It exhibits potent inhibition against these post-prolyl proteases with an IC50 of approximately 1 nM By blocking the enzymatic cleavage of N-terminal Xaa-Pro or Xaa-Ala sequences talabostat mesylate stimulates cytokine and chemokine production enhancing hematopoiesis through induction of colony-stimulating factors such as granulocyte colony-stimulating factor (G-CSF) Due to these activities talabostat serves as a valuable pharmacological tool in studying tumor biology immune modulation and enzyme-mediated signaling pathways
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