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Medchemexpress LLC Taltirelin acetate | 1549593-23-8 | 99.4% | 1 ML
Supplier: Medchemexpress LLC HYB0596A10MM/1ML
Taltirelin acetate (TA-0910) is an acetate form of Taltirelin, an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor superagonist. It can cross the blood-brain barrier and stimulates an increase in cytosolic Ca2+ concentration. This compound has neuroprotective effects in both cellular and animal models of Parkinson's disease and helps alleviate fatigue-like behavior in mouse models of cancer-related fatigue.
- Increases cell viability
- Reduces apoptosis in SH-SY5Y cells
- Inhibits tau phosphorylation and AEP activation
- Improves locomotor function
- Preserves dopaminergic neurons in the substantia nigra
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