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Apexbio Technology LLC Tandospirone citrate 112457-95-1 5mg
Supplier: Apexbio Technology LLC A46565
Tandospirone citrate (CAS 112457-95-1) is a selective partial agonist of the 5-HT1A receptor exhibiting high affinity for this target (Ki 27 nM) while demonstrating markedly lower affinity for other receptors such as 5-HT2 5-HT1C 1 2 D1 and D2 (Ki 1300 41000 nM) In vitro tandospirone citrate shows the strongest binding to 5-HT1A receptors In vivo studies indicate it reduces premature responses in a dose-dependent manner suggesting an inhibitory effect on impulsive behavior Tandospirone citrate is utilized as a pharmacological tool in research on depression anxiety and other neuropsychiatric conditions
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