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Medchemexpress LLC Tanshinone IIA sulfonate sodium | 69659-80-9 | MFCD09028094 | 396.39 | 50 MG
Supplier: Medchemexpress LLC HYN137050MG
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, acting as an inhibitor of store-operated Ca2+ entry (SOCE), and is utilized in the treatment of cardiovascular disorders. It is intended for research use only and is not sold to patients.
- Acts as an inhibitor of store-operated Ca2+ entry (SOCE).
- Used to treat cardiovascular disorders.
- Inhibits hypoxia-induced PKG and PPAR-γ downregulation.
- Suppresses TRPC1 and TRPC6 expression and reverses suppressive effects on basal calcium concentration and SOCE in hypoxic PASMCs.
- Inhibits CYP3A4 activity.
- Attenuates scopolamine-induced cognitive dysfunctions and improves the cholinergic system.
- Increases superoxide dismutase activity and decreases oxidative stress markers.
- Alleviates hypoxia-induced changes in chronic hypoxia PH rat model.
- Prevents peritoneal adhesion.
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