Tanshinone IIA---sulfonic sodium (CAS No 69659-80-9) is a water-soluble derivative of tanshinone IIA primarily used in biomedical research as an anti-inflammatory and anticancer agent Originating from the root of Salvia miltiorrhiza it exerts its effects through modulation of various signaling pathways including NF- B and MAPK leading to apoptosis and reduction of inflammatory responses In vitro activity generally ranges from nanomolar to low micromolar concentrations depending on the assay conditions It is frequently employed in cancer cell lines and inflammatory models to explore its therapeutic potential and mechanisms Animal studies often utilize it to evaluate efficacy and safety as a potential pharmacological agent Experimental concentrations typically depend on the specific research design allowing flexibility for different objectives yet maintaining relevance for drug screening and development purposes