Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502054666

AdipoGen Tanshinone I (5 mg)
SDP

Supplier:  AdipoGen CDXT0417M005

Encompass_Preferred

Chemical. CAS: 568-73-0. Formula: C18H12O3. MW: 276.29. Isolated from plant source. Tanshinone I is a diterpene that has been found in S. miltiorrhiza and has diverse biological activities, including anticancer, antidiabetic, anti-inflammatory, immunosuppressive, anticoagulant and neuroprotective properties. It inhibits proliferation in a variety of cancer cell lines, including KB/VCR, MCF-7/ADR, and K562/A02 multidrug resistance cell lines. It inhibits topoisomerase I- and topoisomerase II-mediated supercoiled DNA relaxation activity. It has been shown to induce apoptosis in several cancer cell lines. It reduces plasma levels of total cholesterol, triglycerides, LDL and nonesterified fatty acids and decreases blood glucose levels in a rat model of type 2 diabetes induced by streptozotocin and a high-fat diet. Tanshinone I reduces the LPS-induced expression of TNF-alpha, IL-1beta, and IL-6 in microglia in vitro.

Catalog No. 50-205-4666


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.