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AdipoGen TAPBPL hFc hrec
Supplier: AdipoGen AG40B02173050
Recombinant Protein. The extracellular domain of human TAPBPL aa 19-405 is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. T cells play critical roles in the adaptive immune system, protecting the human body against cancer, bacterial, viral, fungal and parasitic infections. T cell immune response is tightly controlled by immune checkpoint proteins that negatively or positively regulate T cell response. Among the immune checkpoint proteins, the B7 family plays a key role in controlling immune responses and belongs to the immunoglobulin Ig superfamily. A number of B7 family ligands have been identified, such as B7-1 CD80, B7-2 CD86, PD-L1 B7-H1, PD-L2 B7-DC, B7-H2 inducible T cell co-stimulator ligand ICOS, B7-H3, B7-H4 B7x, B7S1, B7-H5 VISTA and B7- H6. Because of the potential clinical applications of immune checkpoint proteins, there has been intense interest in identifying additional T-cell regulators.
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