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Medchemexpress LLC Taprenepag isopropyl | 1005549-94-9 | 99.0% | 520.60 | 1 ML

Supplier: Medchemexpress LLC HY1999810MM/1ML
Taprenepag isopropyl is a highly selective EP2 receptor agonist. It reduces intraocular pressure (IOP) in the right (dosed) eye in a dose-dependent manner in cynomolgus monkeys. In a high-dose group (0.75 mg/day), IOP was reduced to less than 4 mm Hg on Days 22 and 29. No clinical signs or changes in body weight were observed with any dose, and no ocular findings occurred in the low-dose group (0.75 mg/day).
- Highly selective EP2 receptor agonist.
- Reduces intraocular pressure (IOP) in a dose-dependent manner.
- Achieved IOP reduction to less than 4 mm Hg in high-dose group.
- No clinical signs or changes in body weight observed.
- No ocular findings occurred in the low-dose group.
- Target: EP2.
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