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Medchemexpress LLC Tarloxotinib bromide | 1636180-98-7 | 98.8% | 681.77 | 10 MG
SDP

Catalog No. 5000365520
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Tarloxotinib bromide is an irreversible EGFR/HER2 inhibitor intended for research use only. It is metabolized efficiently under hypoxia in human NSCLC cell lines, a process inhibited by oxygen. This product demonstrates greater activity compared with erlotinib.

  • Irreversible EGFR/HER2 inhibitor.
  • Hypoxia-activated.
  • Effective in inhibiting WT EGFR in vivo.
  • Shown to be metabolized efficiently under hypoxia.
  • Overcomes erlotinib-resistance in preclinical NSCLC models.
  • Associated with tumor regression and durable inhibition of WT EGFR tumor phosphorylation in xenograft models.

Catalog No. 50-003-65520 Supplier Medchemexpress LLC Supplier No. 10MGHY17632
May include imposed supplier surcharges.
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Tarloxotinib bromide is an irreversible EGFR/HER2 inhibitor intended for research use only. It is metabolized efficiently under hypoxia in human NSCLC cell lines, a process inhibited by oxygen. This product demonstrates greater activity compared with erlotinib.

  • Irreversible EGFR/HER2 inhibitor.
  • Hypoxia-activated.
  • Effective in inhibiting WT EGFR in vivo.
  • Shown to be metabolized efficiently under hypoxia.
  • Overcomes erlotinib-resistance in preclinical NSCLC models.
  • Associated with tumor regression and durable inhibition of WT EGFR tumor phosphorylation in xenograft models.

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