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Medchemexpress LLC Tarloxotinib bromide | 1636180-98-7 | 98.8% | 681.77 | 50 MG
Supplier: Medchemexpress LLC HY1763250MG
Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor. It functions as a hypoxia-activated irreversible EGFR-TKI, demonstrating greater activity than erlotinib and exhibiting the therapeutic index necessary to inhibit WT EGFR in vivo, as evidenced by its ability to regress WT EGFR NSCLC tumor models. This product is intended for research use only.
- Irreversible EGFR/HER2 inhibitor
- Hypoxia-activated EGFR-TKI
- Greater activity compared with erlotinib
- Capable of regressing WT EGFR NSCLC tumor models
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