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Medchemexpress LLC TAS-119 | 1453099-83-6 | 98.0% | 506.36 | 25 MG
Supplier: Medchemexpress LLC 25MGHY137377
TAS-119 is a potent, selective, and orally active Aurora A inhibitor. It exhibits an IC50 of 1.0 nM for Aurora A and 95 nM for Aurora B. This compound has demonstrated potent antitumor activities, enhancing the antiproliferative effect of Paclitaxel in various human cancer cell lines, including drug-resistant ones.
- Potent, selective, and orally active Aurora A inhibitor
- IC50 of 1.0 nM for Aurora A
- High selectivity over Aurora B (IC50 of 95 nM)
- Demonstrates potent antitumor activities
- Enhances antiproliferative effect of Paclitaxel
- Induces mitotic accumulation in tumor cells
- For research use only
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