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Medchemexpress LLC Tat-NR2B9c TFA | 1834571-04-8 | 99.7% | 2632.90 | 25 MG

Supplier: Medchemexpress LLC 25MGHYP0117A
Tat-NR2B9c TFA is a potent inhibitor of postsynaptic density-95 (PSD-95). It selectively disrupts the interaction between PSD-95 and NMDAR, inhibiting the binding of NR2A and NR2B to PSD-95. This compound also inhibits the interaction between neuronal nitric oxide synthase (nNOS) and PSD-95, demonstrating significant neuroprotective efficacy.
- Potent PSD-95 inhibitor with high affinity for PSD-95d2 (EC50 6.7 nM)
- Inhibits NMDAR2A, NMDAR2B, and NMDAR2C binding to PSD-95
- Blocks interaction between PSD-95 and nNOS
- Reduces infarction volume in vivo
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