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Medchemexpress LLC Taurocholic acid sodium (sodium taurocholate; N-choloyltaurine sodium) | 145-42-6 | 537.68 | 500 MG
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Supplier:  Medchemexpress LLC HYN0545500MG

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Taurocholic acid sodium has marked bioactive effects, including an inhibitory potential against hepatic artery ligation-induced biliary damage through the upregulation of VEGF-A expression. It also exhibits an immunoregulation effect.

  • Decreases the proportion of CD3+CD8+ T and NK cells in isolated PBMCs from HBeAg-positive CHB patients.
  • Decreases IFN-α stimulated cytokine and cytotoxic granule levels (IFN-γ, TNF-α, granzyme B) in CD3+CD8+ T and NK cells.
  • Promotes HBV replication by reducing the percentage of NK and CD3+CD8+ T cells in C57BL/6 mice with tail vein injection with rAAV8-1.3HBV.
  • Prevents hepatic artery ligation (HAL)-induced cholangiocyte damage in rats by upregulation of VEGF-A expression.

Catalog No. 50-003-89055


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