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Medchemexpress LLC Taurolithocholic acid | 516-90-5 | 99.7% | 483.70 | 10 MG
Supplier: Medchemexpress LLC HY11330810MG
Taurolithocholic acid is an orally active bile acid and antiviral agent. It functions by upregulating FADS2 through the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibiting SFTSV-induced ferroptosis, viral replication, and viral entry of HBV/HDV. It also reduces the release of IL-1β, lipid ROS, and LDH. This compound serves as an experimental model for hepatocellular cholestasis and offers protection against lethal SFTSV infection in mice, making it suitable for related research.
- Orally active bile acid and antiviral agent
- Upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis
- Inhibits SFTSV-induced ferroptosis, viral replication, and viral entry of HBV/HDV
- Reduces the release of IL-1β, lipid ROS, and LDH
- Experimental model compound for hepatocellular cholestasis
- Protects mice from lethal SFTSV infection
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