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Cayman Chemical TaurolIthocholIc AcIdodIM 10mg
Supplier: Cayman Chemical 1727510 MG
A taurine-conjugated form of lithocholic acid; increases caspase-3 and -7 activity in NTCP-transfected Hep3B cells at 75 µM; has been used to induce cholestasis in ex vivo and in vivo animal models of hepatocellular cholestasis; serum levels of TLCA increase approximately 5-fold in within two hours during an oral lipid tolerance test in humans
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