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Medchemexpress LLC Tazarotene (AGN 190168) | 118292-40-3 | C21H21NO2S | 5 MG
Supplier: Medchemexpress LLC HY153885MG
Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist used for treating plaque psoriasis and acne vulgaris. It is also a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Used for monotherapy or adjuvant therapy for psoriasis and acne
- Upregulates tumor suppressor tazarotene induced gene 3
- Suppresses gene expression of MRP-8 and SKALP in human epidermal cell cultures
- Delivered into the skin via topical gel application
- Metabolized to active tazarotenic acid with short systemic residence time
- Blocks induction of ornithine decarboxylase activity
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