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AdipoGen TBB
SDP

Supplier:  AdipoGen AGCR13660M025

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Chemical. CAS 17374-26-4. Formula C6HBr4N3. MW 434.7. Synthetic. ATP/GTP-competitive cell permeable casein kinase II CK2 inhibitor IC50=0.9µM for rat liver. Less potently inhibits CCK2/cyclin A, GSK3beta and phosphorylase kinase IC50=15.6, 11.2 and 8.7µM, respectively. Binds to the Val66 residue of CK2 and inhibits the binding of ATP/GTP. Moderate DYRK1A inhibitor IC50=4.4µM. Induces caspase-dependent apoptosis and degrades hematopoietic lineage cell-specific protein 1 HS1 in Jurkat cells.

Catalog No. 50-256-2246


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