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AdipoGen TBB (5 mg)

Supplier: AdipoGen AGCR13660M005
TBB (5 mg), AdipoGen Life Sciences. Chemical. CAS: 17374-26-4. Formula: C6HBr4N3. MW: 434.7. Synthetic. ATP/GTP-competitive cell permeable casein kinase II (CK2) inhibitor (IC50=0.9µM for rat liver. Less potently inhibits CCK2/cyclin A, GSK3beta and phosphorylase kinase (IC50=15.6, 11.2 and 8.7µM, respectively). Binds to the Val66 residue of CK2 and inhibits the binding of ATP/GTP. Moderate DYRK1A inhibitor (IC50=4.4µM). Induces caspase-dependent apoptosis and degrades hematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.
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