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Cayman Chemical TC 14012trIfluoROCTAte sa 10mg
Supplier: Cayman Chemical 1197410 MG
A CXCR4 antagonist (IC50 = 2.9 nM) and CXCR7 agonist; induces β-arrestin recruitment in HEK293T cells expressing CXCR7 (EC50 = 350 nM); reduces the cytopathic effect of HIV in infected MT-4 cells (EC50 = 0.4 nM); inhibits HIV entry in vitro in a CXCR4-dependent manner (IC50 = 19.3 nM); inhibits CXCL12-induced migration in MDA-MB-231 cells and HUVECs from 10-1,000 nM; decreases infarct size in a mouse model of LAD coronary artery ligation-induced acute myocardial infarction at 10 mg/kg
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