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Apexbio Technology LLC TC-E 5003 17328-16-4 50mg
Supplier: Apexbio Technology LLC B775050
TC-E 5003 (CAS 17328-16-4) is a selective inhibitor of protein arginine methyltransferase 1 (PRMT1) exhibiting an IC50 of 1 5 M1 PRMT1 a member of the PRMT family mediates post-translational arginine methylation and is implicated in regulating diverse cellular processes Aberrant PRMT1 activity has been associated with a range of malignancies making it of interest for oncology research In cellular studies TC-E 5003 has been shown to inhibit proliferation and induce apoptosis in MCF7a breast cancer and LNCaP prostate cancer cell lines as well as attenuate androgen-induced gene expression in LNCaP cells This compound serves as a useful tool for investigating PRMT1 function and its role in cancer biology
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