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Cayman Chemical TCN 237hydrochlorIde 10mg
Supplier: Cayman Chemical 4226610 MG
An NR2B subunit-containing NMDA receptor antagonist (Ki = 0.85 nM); selectively inhibits glutamate and glycine-induced currents in whole-cell patch-clamp assays using L-M(TK-) cells expressing NR2B subunit-containing NMDA receptors over L-M(TK-) cells expressing NR2A- or NR2D subunit-containing NMDA receptors and HEK293 cells expressing NR2C subunit-containing NMDA receptors; inhibits carrageenan-induced mechanical hyperalgesia in rats at 3 mg/kg
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