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Medchemexpress LLC TCO-PEG-TCO | 97.1% | 25 MG
Supplier: Medchemexpress LLC 25MGHY140731
TCO-PEG-TCO is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, incorporating a TCO group that can engage in an inverse electron demand Diels-Alder reaction (iEDDA) with molecules possessing Tetrazine groups. PROTACs, composed of two distinct ligands connected by a linker, target an E3 ubiquitin ligase and a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Utilized in PROTAC synthesis
- Functions as a click chemistry reagent
- Incorporates a TCO group
- Engages in inverse electron demand Diels-Alder reaction (iEDDA)
- Leverages the intracellular ubiquitin-proteasome system
- For selective degradation of target proteins
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