Medchemexpress LLC TCO-PEG-TCO (MW 5000) | 97.1% | 50 MG

Supplier:  Medchemexpress LLC HY14073150MG

TCO-PEG-TCO (MW 5000) is a PEG-based PROTAC linker, a click chemistry reagent containing a TCO group that undergoes an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine groups. It is utilized in the synthesis of PROTACs, which consist of two ligands connected by a linker-one targeting an E3 ubiquitin ligase and the other a protein of interest. These compounds leverage the intracellular ubiquitin-proteasome system to facilitate selective degradation of target proteins. This product has an average molecular weight of 5000 and appears as a white to off-white solid.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Functions as a click chemistry reagent
• Contains a TCO group for iEDDA reaction with tetrazine groups
• Facilitates selective degradation of target proteins
• Molecular weight: 5000 (average)
• Appearance: Solid
• Color: White to off-white
• For research use only

Catalog No. 50-003-56653