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Medchemexpress LLC TCO-PEG-TCO (MW 5000) | 97.1% | 50 MG
SDP

Catalog No. 5000356653
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TCO-PEG-TCO (MW 5000) is a PEG-based PROTAC linker, a click chemistry reagent containing a TCO group that undergoes an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine groups. It is utilized in the synthesis of PROTACs, which consist of two ligands connected by a linker-one targeting an E3 ubiquitin ligase and the other a protein of interest. These compounds leverage the intracellular ubiquitin-proteasome system to facilitate selective degradation of target proteins. This product has an average molecular weight of 5000 and appears as a white to off-white solid.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Functions as a click chemistry reagent
  • Contains a TCO group for iEDDA reaction with tetrazine groups
  • Facilitates selective degradation of target proteins
  • Molecular weight: 5000 (average)
  • Appearance: Solid
  • Color: White to off-white
  • For research use only

Catalog No. 50-003-56653 Supplier Medchemexpress LLC Supplier No. HY14073150MG
May include imposed supplier surcharges.
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TCO-PEG-TCO (MW 5000) is a PEG-based PROTAC linker, a click chemistry reagent containing a TCO group that undergoes an inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine groups. It is utilized in the synthesis of PROTACs, which consist of two ligands connected by a linker-one targeting an E3 ubiquitin ligase and the other a protein of interest. These compounds leverage the intracellular ubiquitin-proteasome system to facilitate selective degradation of target proteins. This product has an average molecular weight of 5000 and appears as a white to off-white solid.

  • PEG-based PROTAC linker
  • Used in the synthesis of PROTACs
  • Functions as a click chemistry reagent
  • Contains a TCO group for iEDDA reaction with tetrazine groups
  • Facilitates selective degradation of target proteins
  • Molecular weight: 5000 (average)
  • Appearance: Solid
  • Color: White to off-white
  • For research use only

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