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Medchemexpress LLC TCO-PEG4-NHS ester | 1621096-79-4 | 99.2% | C24H38N2O10 | 50 MG
Supplier: Medchemexpress LLC HY141167A50MG
TCO-PEG4-NHS ester is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It also functions as a click chemistry reagent, capable of undergoing an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. This reagent facilitates the creation of PROTACs, which leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains a TCO group
- Undergoes inverse electron demand Diels-Alder reaction (iEDDA) with Tetrazine groups
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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