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Medchemexpress LLC TCO-PEG4-VC-PAB-MMAE | 2758671-45-1 | 99.3% | 1522.91 g/mol | C78H127N11O19 | 5 MG
SDP

Catalog No. 5000202114
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TCO-PEG4-VC-PAB-MMAE is an antibody-drug conjugate (ADC) drug-linker conjugate that combines a cleavable valine-citrulline-para-aminobenzyl (VC-PAB) linker with the cytotoxic payload monomethyl auristatin E (MMAE). It contains a trans-cyclooctene (TCO) group for inverse-electron-demand Diels-Alder (iEDDA) click conjugation to tetrazine-functionalized molecules and is supplied as a solid for ADC research and bioconjugation workflows.

  • Contains TCO group for iEDDA click chemistry.
  • Cleavable valine-citrulline-PAB linker enabling controlled payload release.
  • MMAE payload with potent tubulin inhibitory activity.
  • High purity suitable for research applications.
  • Storage: solid at -20°C; protect from light.

Catalog No. 50-002-02114 Supplier Medchemexpress LLC Supplier No. HY1480575MG
May include imposed supplier surcharges.
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TCO-PEG4-VC-PAB-MMAE is an antibody-drug conjugate (ADC) drug-linker conjugate that combines a cleavable valine-citrulline-para-aminobenzyl (VC-PAB) linker with the cytotoxic payload monomethyl auristatin E (MMAE). It contains a trans-cyclooctene (TCO) group for inverse-electron-demand Diels-Alder (iEDDA) click conjugation to tetrazine-functionalized molecules and is supplied as a solid for ADC research and bioconjugation workflows.

  • Contains TCO group for iEDDA click chemistry.
  • Cleavable valine-citrulline-PAB linker enabling controlled payload release.
  • MMAE payload with potent tubulin inhibitory activity.
  • High purity suitable for research applications.
  • Storage: solid at -20°C; protect from light.

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