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Medchemexpress LLC Tco-PEG5-maleimide | 00-00-0 | 99.5% | C28H45N3O10 | 10MG
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Supplier:  Medchemexpress LLC HY13347510MG

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TCO-PEG5-maleimide is a PEG-based PROTAC linker and click-chemistry reagent that combines a maleimide reactive group with a PEG5 spacer bearing a trans-cyclooctene (TCO) moiety. It is designed for efficient bioorthogonal conjugation and thiol-selective coupling in PROTAC synthesis and bioconjugation workflows, provided as a high-purity solid with recommended low-temperature storage for stability.

  • Enables rapid bioorthogonal conjugation via TCO-tetrazine click chemistry.
  • Maleimide group allows thiol-selective conjugation to cysteine residues or thiol-containing linkers.
  • PEG5 spacer improves aqueous solubility and reduces steric hindrance.
  • High chemical purity suitable for synthesis and analytical applications.
  • Available in multiple small-scale package sizes for research use.
  • Stable when stored dry at low temperature; in solution requires colder storage for extended stability.

Catalog No. 50-002-62011


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