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Cayman Chemical TDFAtrIfluoroacetate salt 10mg
Supplier: Cayman Chemical 2248410 MG
An inhibitor of JNK (IC50 280 nM) competitive for JNK1 binding with pepJIP1 (IC50 500 nM) selective for JNK over p38a mTOR and PI3Ka inhibits c-Jun phosphorylation induced by TNF-a (EC50 12 4 UM) restores insulin sensitivity in a mouse model of type 2 diabetes when administered at 25 mg/kg 30 minutes prior to insulin reduces human prostate strip contractions induced by phenylephrine or norepinephrine when applied at 30 UM and reduces phosphorylation of c-Jun a JNK substrate
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