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Cayman Chemical TebIpenmhydrate 100mg
SDP

Supplier:  Cayman Chemical 33875100 MG

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A STING agonist binds to wild-type and HAQ variant STING in a 3H-cGAMP filtration binding assay (EC50s 2.48 and 1.72 M respectively) induces secretion of IFN-B from THP-1 cells by 129 relative to induction by 23-cGAMP at 30 M reduces tumor growth in an MC-38 syngeneic mouse model of colon carcinoma in a dose-dependent manner and induces tumor regression at 450 g intratumorally and 50 mg/kg s.c. acts synergistically with an anti-PD-1 antibody in MC-38 CT26 B16/F10 and LL/2 syngeneic mouse models

Catalog No. 50-294-6754


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