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Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 G
Supplier: Medchemexpress LLC HY14153A1G
Tegaserod maleate is an orally active compound that functions as a serotonin receptor 4 agonist and a serotonin receptor 2B antagonist. It demonstrates inhibitory activity against 5-HT2A, 5-HT2B, and 5-HT2C receptors. This compound has been observed to induce apoptosis in tumor cells, inhibit PI3K/Akt/mTOR signaling, and reduce S6 phosphorylation. It shows promise for anti-tumor applications and research into irritable bowel syndrome.
- Orally active serotonin receptor 4 agonist.
- Serotonin receptor 2B antagonist.
- Induces tumor cell apoptosis.
- Inhibits PI3K/Akt/mTOR signaling and decreases S6 phosphorylation.
- Exhibits anti-tumor activity, delays tumor growth, reduces metastases, and increases survival.
- Potential for irritable bowel syndrome research.
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