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Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 ML
Supplier: Medchemexpress LLC HY14153A10MM/1ML
Tegaserod maleate is an orally active serotonin receptor 4 (HTR4) agonist and a 5-HT2B receptor antagonist. It demonstrates anti-tumor activity by inducing tumor cell apoptosis and blunting PI3K/Akt/mTOR signaling. It is also being researched for its potential in treating irritable bowel syndrome (IBS) and diabetic gastropathy.
- Potent agonist of 5-HT4 receptor
- Antagonist of 5-HT2B receptor
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Accelerates gastric emptying rate
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